Publications

20. The rational redesign of penicillins to help combat penicillin resistance: Timothy J. Snape and Alison M. Astles, The Pharmaceutical Journal 2010; 285: 162.

19. Take a close look at citalopram and you can predict its contraindications: Timothy J. Snape and Alison M. Astles, The Pharmaceutical Journal 2010; 285: 59 - Cover Article.


18. Effects of Momordica charantia fruit extract with the combination of temozolamide and cisplatin in the treatment of glioma cancer: G. Manoharan, R. W. Lea, T. J. Snape, J. Singh, Proc. Physiol. Soc., 2010, 18, PC22.

17. Towards a chemo-enzymatic method for the asymmetric synthesis of β-amino tertiary alcohols: Andrea March-Cortijos and Timothy J. Snape*, Org. Biomol. Chem., 2009, 7, 5163-5165.

16. Monoamine Oxidase (MAO-N) Catalysed Reactions: Application Towards the Chemo-Enzymatic Deracemisation of the Alkaloid (±)-Crispine A: Andrew J. Ellis, Renate Reiss, Timothy J. Snape and Nicholas J. Turner, Practical Methods for Biocatalysis and Biotransformations, 2009, John Whittall, Peter Sutton (Eds), Wiley, Chapter 11.1.


15. Versatility of a new bioinorganic catalyst: Palladized cells of Desulfovibrio desulfuricans and application to dehalogenation of flame retardant materials, K. Deplanche;  T. J. Snape;  S. Hazrati;  S. Harrad; L. E. Macaskie*, Environmental Technology, 2009, 30, 7, 681–692.

14. Helix Persistence and Breakdown in Oligoureas of Metaphenylenediamine: Apparent Diastereotopicity as a Spectroscopic Marker of Helix Length in Solution: Jonathan Clayden*, Loic Lemiegre, Gareth A. Morris, Mark Pickworth, Timothy J. Snape and Lyn H. Jones, J. Am. Chem. Soc., 2008, 130, 15193–15202.

 
13. α-Arylation of Aryl-Ketones: Expanding the Scope of the Truce-Smiles Rearrangement: Timothy J. Snape*, Synlett, 2008, 2689-2691.

 
12. A Truce on the Smiles Rearrangement: Revisiting an Old Reaction – The Truce-Smiles Rearrangement: Timothy J. Snape*, Chem. Soc. Rev., 2008, 11, 2452-2458.

11. A biogenic catalyst for hydrogenation, reduction and selective dehalogenation in non-aqueous solvents: N. J. Creamer, K. Deplanche, T. J. Snape, I. P. Mikheenko, P. Yong, D. Samyahumbi, J. Wood, K. Pollmann, S. Selenska-Pobell and L. E. Macaskie*, Hydrometallurgy, 2008, 94, 138-143.

10. Enzymatic desymmetrisation of (2-hydroxymethyl-oxiranyl)-methanol in organic solvents: Andrea March Cortijos and Timothy J. Snape*, Tetrahedron: Asymmetry, 2008, 19, 15, 1761-1763.

9. Recent Advances in the Semi-Pinacol Rearrangement of α-Hydroxy Epoxides and Related Compounds: Timothy J. Snape*, Chem. Soc. Rev., 2007, 36, 11, 1823-1842.

 


8. A Template-Based Mnemonic for Monoamine Oxidase (MAO-N) Catalyzed Reactions and its Application Towards the Chemo-Enzymatic Deracemisation of the Alkaloid (±)-Crispine A: Kevin R. Bailey, Andrew J. Ellis, Renate Reiss, Timothy J. Snape* and Nicholas J. Turner*, Chem. Commun., 2007, 3640-3642. Designated a Chem. Commun. “Hot Article”


7. Achieving conformational control over C-C, C-N and C-O bonds in biaryls, N,N’-diarylureas and diaryl ethers: advantages of a relay axis: Mark S. Betson, Ann Bracegirdle, Jonathan Clayden*, Madeleine Helliwell, Andrew Lund, Mark Pickworth, Timothy J. Snape and Christopher P. Worrall, Chem. Commun., 2007, 7, 754-756.


6. Application of the Semi-Pinacol Rearrangement Towards the Generation of Alkenyl-Substituted Quaternary Carbon Centres: Timothy J. Snape*, Org. Biomol. Chem., 2006, 4, 4144-4148.


5. Induction of Apoptosis in Estrogen-Receptor Negative Breast Cancer Cells by Natural and Synthetic Cyclopentenones: Role of the IKK/NF-κB Pathway: Ciucci A, Gianferretti P, Piva R, Guyot T, Snape TJ, Roberts SM and Santoro MG*, Mol. Pharmacol., 2006, 70, 1812-1821.

4. Synthesis of 4-azacyclopent-2-enones and 5,5-dialkyl-4-azacyclopent-2-enones: Dauvergne J, Happe AM*, Jadhav V, Justice D, Matos MC, McCormack PJ, Pitts MR, Roberts SM, Singh SK, Snape TJ, Whittall J, Tetrahedron, 2004, 60, 2559-2567.


3. Synthesis and revision of the stereochemistry of a cyclopentenone natural product isolated from ascomycete strain A23-98:Bickley JF, Roberts SM, Santoro AG, Snape TJ*, Tetrahedron, 2004, 60, 2569-2576.


2. The IκB kinase IKK is the molecular target for anti-herpetic cyclopentenones: Amici C, Belardo G, Ciucci A, Volpi C, Guyot T, Evans P, Happe A, Snape T, Roberts S, Santoro MG*, Antiviral Research, 2003, 57, 3, A58-A58.

1. Patent: Roberts Stanley Michael; Ross Nicolette Christa; Jadhav Vasudev; Evans Paul; Snape Timothy James; Happe Alan Michael; Santoro Gabriella Maria, Patent Number: AU2003224244, Publication Date: 2003-10-13, Charterhouse Therapeutics Ltd.